产品货号：
Z37094
中文名称：
RIG-1/DDX58抗体
英文名称：
Anti-RIG-1/DDX58 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-RIG-1/DDX58 Antibody |
| 指标别名 | DDX58;DEAD box protein 58;RIG 1;RIG I;RIG-I |
| 克隆性 | Monoclonal |
| 检验物种 | human |
| 应用范围 | WB |
| 基因名称 | DDX58 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human DDX58 Retinoic acid inducible gene I (RIG-I) is a 925 amino acid,interferon-inducible cellular DExD/H box RNA helicase that activates type I interferon (IFN),an important effector of the innate immune system that is sensitive to these dsRNA viruses.dsRNA is normally present in very low quantities in cells,so when a virus is present,the elevated levels of dsRNA act as a sign telling RIG-I to activate the production of IFN. |
| 实际分子量 | 107KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | RIG-I (retinoic acid-inducible gene I) is a RIG-I-like receptor dsRNA helicase enzyme that is encoded (in humans) by the DDX58 gene.RIG-I is part of the RIG-I-like receptor family,which also includes MDA5 and LGP2,and functions as a pattern recognition receptor that is a sensor for viruses such as influenza A,Sendai virus,and flavivirus.DEAD box proteins,characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD),are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure.This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD).It is involved in viral double-stranded (ds) RNA recognition and the regulation of immune response. |
| Uniprot ID | O95786 |
| 推荐稀释比 | Western blot (WB) 1:400～800 |
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